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Novel hantavirus in the flat-skulled shrew (Sorex roboratus).

ABSTRACT: Genetically distinct hantaviruses have been identified recently in multiple species of shrews (Order Soricomorpha, Family Soricidae) in Eurasia and North America. To corroborate decades-old reports of hantaviral antigens in shrews from Russia, archival liver and lung tissues from 4 Siberian large-toothed shrews (Sorex daphaenodon), 5 Eurasian least shrews (Sorex minutissimus), 12 flat-skulled shrews (Sorex roboratus), and 18 tundra shrews (Sorex tundrensis), captured in the Sakha Republic in northeastern Siberia during July and August 2006, were analyzed for hantavirus RNA by reverse transcription-polymerase chain reaction. A novel hantavirus, named Kenkeme virus, was detected in a flat-skulled shrew. Sequence analysis of the full-length S and partial M and L segments indicated that Kenkeme virus was genetically and phylogenetically distinct from Seewis virus harbored by the Eurasian common shrew (Sorex araneus), as well as all other rodent-, soricid-, and talpid-borne hantaviruses.

SUBMITTER: Kang HJ

PROVIDER: S-EPMC2979330 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature

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Novel hantavirus in the flat-skulled shrew (Sorex roboratus).

Kang Hae Ji HJ Arai Satoru S Hope Andrew G AG Cook Joseph A JA Yanagihara Richard R

Vector borne and zoonotic diseases (Larchmont, N.Y.) 20100801 6

Genetically distinct hantaviruses have been identified recently in multiple species of shrews (Order Soricomorpha, Family Soricidae) in Eurasia and North America. To corroborate decades-old reports of hantaviral antigens in shrews from Russia, archival liver and lung tissues from 4 Siberian large-toothed shrews (Sorex daphaenodon), 5 Eurasian least shrews (Sorex minutissimus), 12 flat-skulled shrews (Sorex roboratus), and 18 tundra shrews (Sorex tundrensis), captured in the Sakha Republic in nor ...[more]

PMID: 20426682

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Sequencing and analysis of the complete mitochondrial genome of flat-skulled shrew (<i>Sorex roboratus</i>) from China.

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