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2-Amino-5-chloro-pyridine-fumaric acid (1/2).

ABSTRACT: The asymmetric unit of the title compound, C(5)H(5)ClN(2)·0.5C(4)H(4)O(4), comprises a neutral 2-amino-5-chloro-pyridine mol-ecule and one half of a fumaric acid mol-ecule which lies on an inversion center. The dihedral angle between the pyridine ring and the plane formed by the fumaric acid mol-ecule is 3.22?(8)°. The 2-amino-5-chloro-pyridine mol-ecule is planar, with a maximum deviation of 0.004?(1)?Å for the pyridine N atom. In the crystal, the 2-amino-5-chloro-pyridine mol-ecules inter-act with the carboxyl groups of fumaric acid mol-ecules through N-H?O and O-H?N hydrogen bonds, forming centrosymmetric R(2) (2)(8) ring motifs and another N-H?O hydrogen bond links these motifs into a two-dimensional network parallel to (100).

SUBMITTER: Hemamalini M

PROVIDER: S-EPMC2979350 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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2-Amino-5-chloro-pyridine-fumaric acid (1/2).

Hemamalini Madhukar M Fun Hoong-Kun HK

Acta crystallographica. Section E, Structure reports online 20100522 Pt 6

The asymmetric unit of the title compound, C(5)H(5)ClN(2)·0.5C(4)H(4)O(4), comprises a neutral 2-amino-5-chloro-pyridine mol-ecule and one half of a fumaric acid mol-ecule which lies on an inversion center. The dihedral angle between the pyridine ring and the plane formed by the fumaric acid mol-ecule is 3.22 (8)°. The 2-amino-5-chloro-pyridine mol-ecule is planar, with a maximum deviation of 0.004 (1) Å for the pyridine N atom. In the crystal, the 2-amino-5-chloro-pyridine mol-ecules inter-act ...[more]

PMID: 21579495

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