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19-[(E)-4-Chloro-benzyl-idene]-16-(4-chloro-phen-yl)-2-hydr-oxy-1,11-diaza-hexa-cyclo-[15.3.1.0.0.0.0]henicosa-3(8),4,6-triene-9,18-dione.

ABSTRACT: In the title compound, C(32)H(26)Cl(2)N(2)O(3), the piperidone ring adopts a chair conformation and the proline and pyrrolidine rings adopt envelope conformations. The indane ring system is essentially planar with an r.m.s. deviation of 0.011?Å for the non-H atoms. The dihedral angle between the two chloro-substituted benzene rings is 63.69?(10)°. Intra-molecular C-H?O and N-H?O hydrogen bonds may influence the mol-ecular conformation. In the crystal structure, mol-ecules are connected into layers by weak inter-molecular C-H?O hydrogen bonds.

SUBMITTER: Kumar RS

PROVIDER: S-EPMC2979351 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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19-[(E)-4-Chloro-benzyl-idene]-16-(4-chloro-phen-yl)-2-hydr-oxy-1,11-diaza-hexa-cyclo-[15.3.1.0.0.0.0]henicosa-3(8),4,6-triene-9,18-dione.

Kumar Raju Suresh RS Osman Hasnah H Abdul Rahim Aisyah Saad AS Hemamalini Madhukar M Fun Hoong-Kun HK

Acta crystallographica. Section E, Structure reports online 20100526 Pt 6

In the title compound, C(32)H(26)Cl(2)N(2)O(3), the piperidone ring adopts a chair conformation and the proline and pyrrolidine rings adopt envelope conformations. The indane ring system is essentially planar with an r.m.s. deviation of 0.011 Å for the non-H atoms. The dihedral angle between the two chloro-substituted benzene rings is 63.69 (10)°. Intra-molecular C-H⋯O and N-H⋯O hydrogen bonds may influence the mol-ecular conformation. In the crystal structure, mol-ecules are connected into laye ...[more]

PMID: 21579517

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