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4-(3-Methoxy-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide.

ABSTRACT: In the title compound, C(16)H(14)N(4)O(2)S, intra-molecular N-H?N hydrogen bonding forms an S(5) ring, whereas N-H?O and C-H?S inter-actions complete S(6) ring motifs. In the crystal, mol-ecules form inversion dimers due to N-H?O inter-actions. The dimers are inter-linked through N-H?S hydrogen bonds and ?-? inter-actions occur with a centroid-centroid distance of 3.8422?(11)?Å between the meth-oxy-containing benzene ring and the five-membered heterocyclic ring.

SUBMITTER: Pervez H

PROVIDER: S-EPMC2979529 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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4-(3-Methoxy-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide.

Pervez Humayun H Iqbal Mohammad S MS Saira Naveeda N Yaqub Muhammad M Tahir M Nawaz MN

Acta crystallographica. Section E, Structure reports online 20100522 Pt 6

In the title compound, C(16)H(14)N(4)O(2)S, intra-molecular N-H⋯N hydrogen bonding forms an S(5) ring, whereas N-H⋯O and C-H⋯S inter-actions complete S(6) ring motifs. In the crystal, mol-ecules form inversion dimers due to N-H⋯O inter-actions. The dimers are inter-linked through N-H⋯S hydrogen bonds and π-π inter-actions occur with a centroid-centroid distance of 3.8422 (11) Å between the meth-oxy-containing benzene ring and the five-membered heterocyclic ring. ...[more]

PMID: 21579483

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4-(3-Fluoro-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide.

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4-(2-Ethyl-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide.

Project description:The title compound, C(17)H(16)N(4)OS, is stabilized in the form of a two-dimensional polymeric network due to inter-molecular N-H?S and N-H?O hydrogen bonds. An intra-molecular N-H?N hydrogen bond forms an S(5) ring, whereas inter-actions of the N-H?O and C-H?S types complete S(6) ring motifs. ?-? inter-actions with a centroid-centroid distance of 3.6514?(10)?Å are found between the ethyl-substituted benzene ring and the heterocyclic ring of the isatin derivative.

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4-(3-Nitro-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide.

Project description:In the title compound, C(15)H(11)N(5)O(3)S, intra-molecular N-H?N hydrogen bonding forms an S(5) ring motif, whereas N-H?O and C-H?S inter-actions type complete S(6) ring motifs. The 2-oxoindoline and 3-methoxy-phenyl rings are almost planar, with r.m.s. deviations of 0.0178 and 0.0149?Å, respectively, and form a dihedral angle of 33.59?(3)°. In the crystal, mol-ecules are inter-linked through the nitro groups in an end-to-end fashion via N-H?O and C-H?O inter-actions.

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4-(3-Iodo-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide.

Project description:In the title compound, C(15)H(11)IN(4)OS, intra-molecular N-H?N, N-H?O and C-H?S inter-actions generate one S(5) and two S(6) ring motifs. In the crystal, mol-ecules form centrosymmetric dimers via pairs of N-H?O inter-actions, generating R(2) (2)(8) ring motifs. In addition a short inter-molecular I?S contact of 3.352?(3)?Å is observed.

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