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2-{[(4-Methoxy-phen-yl)dimethyl-silyl]meth-yl}isoindoline-1,3-dione.


ABSTRACT: In the course of our studies of silicon-containing anti-cancer compounds, the title compound, C(18)H(19)NO(3)Si, was synthesized. The mol-ecular geometry including bond distances and angles involving the Si atoms are typical. Torsion angles associated with the isoindoline ring and the silyl group [C-N-C(methyl-ene)-Si = 90.5?(2) and -93.1?(2)°] indicate that there is no inter-action between the O and Si atoms despite silicon's high affinity for oxygen.

SUBMITTER: Guzei IA 

PROVIDER: S-EPMC2980072 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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2-{[(4-Methoxy-phen-yl)dimethyl-silyl]meth-yl}isoindoline-1,3-dione.

Guzei Ilia A IA   Spencer Lara C LC   Zakai Uzma I UI  

Acta crystallographica. Section E, Structure reports online 20091224 Pt 1


In the course of our studies of silicon-containing anti-cancer compounds, the title compound, C(18)H(19)NO(3)Si, was synthesized. The mol-ecular geometry including bond distances and angles involving the Si atoms are typical. Torsion angles associated with the isoindoline ring and the silyl group [C-N-C(methyl-ene)-Si = 90.5 (2) and -93.1 (2)°] indicate that there is no inter-action between the O and Si atoms despite silicon's high affinity for oxygen. ...[more]

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