6-(4-Bromo-phen-yl)-2-eth-oxy-4-(4-ethoxy-phen-yl)nicotinonitrile.

ABSTRACT: The mol-ecule of the title nicotinonitrile derivative, C(22)H(19)BrN(2)O(2), is non-planar, the central pyridine ring making dihedral angles of 7.34?(14) and 43.56?(15)° with the 4-bromo-phenyl and 4-ethoxy-phenyl rings, respectively. The eth-oxy group of the 4-ethoxy-phenyl is slightly twisted from the attached benzene ring [C-O-C-C = 174.2?(3)°], whereas the eth-oxy group attached to the pyridine ring is in a (+)syn-clinal conformation [C-O-C-C = 83.0?(3)°]. A weak intra-molecular C-H?N inter-action generates an S(5) ring motif. In the crystal structure, the mol-ecules are linked by weak inter-molecular C-H?N inter-actions into screw chains along the b axis. These chains stacked along the a axis. ?-? inter-actions with centroid-centroid distances of 3.8724?(16) and 3.8727?(16)?Å are also observed.

SUBMITTER: Chantrapromma S 

PROVIDER: S-EPMC2980143 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature