Ontology highlight
ABSTRACT:
SUBMITTER: Cluzel ME
PROVIDER: S-EPMC2981194 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Cluzel Marie-Eve ME Zanella-Cléon Isabelle I Cozzone Alain J AJ Fütterer Klaus K Duclos Bertrand B Molle Virginie V
Journal of bacteriology 20100924 23
The Staphylococcus aureus autoinducer-2 (AI-2) producer protein LuxS is phosphorylated by the Ser/Thr kinase Stk1 at a unique position, Thr14. The enzymatic activity of the phosphorylated isoform of LuxS was abrogated compared to that of nonphosphorylated LuxS, thus providing the first evidence of an AI-2-producing enzyme regulated by phosphorylation and demonstrating that S. aureus possesses an original and specific system for controlling AI-2 synthesis. ...[more]