Ontology highlight
ABSTRACT:
SUBMITTER: Strouse JJ
PROVIDER: S-EPMC2981471 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Strouse John J JJ Reller Megan E ME Bundy David G DG Amoako Martha M Cancio Maria M Han Rachel N RN Valsamakis Alexandra A Casella James F JF
Blood 20100723 18
Influenza causes excess morbidity in sickle cell disease (SCD). H1N1 pandemic influenza has been severe in children. To compare H1N1 with seasonal influenza in SCD (patients younger than 22), we reviewed medical records (1993-2009). We identified 123 cases of laboratory-confirmed influenza (94 seasonal, 29 H1N1). Those with seasonal influenza were younger (median 4.4 vs 8.7 years old, P = .006) and had less asthma (24% vs 56%, P = .002). Those with H1N1 influenza more often had acute chest syndr ...[more]