Ontology highlight
ABSTRACT:
SUBMITTER: Jotani MM
PROVIDER: S-EPMC2983585 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Structure reports online 20100213 Pt 3
In the title compound, C(24)H(22)N(2)O(4)S, the central pyrimidine ring is significantly puckered, assuming a conformation inter-mediate between a boat and a screw boat. The nearly planar thia-zole ring (r.m.s. deviation = 0.0258 Å) is fused with the pyriamidine ring, making a dihedral angle of 9.83 (7)°. The carboxyl group is in an extended conformation with an anti-periplanar orientation with respect to the dihydropyrimidine ring. The benzene ring linked at the chiral C atom is perpendicular t ...[more]