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(6R)-2-tert-Butyl-6-[(4R,5S)-3-isopropyl-4-methyl-5-phenyl-oxazolidin-2-yl]phenol.

ABSTRACT: In the title compound, C(23)H(31)NO(2), the lone pair on the nitro-gen atom is oriented to facilitate intra-molecular hydrogen bonding with the hydr-oxy group residing on the phenyl substituent. The five-membered ring adopts an envelope confornmation with the O atom at the flap. The absolute stereochemistry was verified by measurement of optical activity using a digital polarimeter.

SUBMITTER: Koyanagi T

PROVIDER: S-EPMC2983796 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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(6R)-2-tert-Butyl-6-[(4R,5S)-3-isopropyl-4-methyl-5-phenyl-oxazolidin-2-yl]phenol.

Koyanagi Takaoki T Edler Kate L KL Parrott Raleigh W RW Hitchcock Shawn R SR Ferrence Gregory M GM

Acta crystallographica. Section E, Structure reports online 20100324 Pt 4

In the title compound, C(23)H(31)NO(2), the lone pair on the nitro-gen atom is oriented to facilitate intra-molecular hydrogen bonding with the hydr-oxy group residing on the phenyl substituent. The five-membered ring adopts an envelope confornmation with the O atom at the flap. The absolute stereochemistry was verified by measurement of optical activity using a digital polarimeter. ...[more]

PMID: 21580714

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