Ontology highlight
ABSTRACT:
SUBMITTER: Haugarvoll K
PROVIDER: S-EPMC2986168 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Haugarvoll Kristoffer K Toft Mathias M Skipper Lisa L Heckman Michael G MG Crook Julia E JE Soto Alexandra A Ross Owen A OA Hulihan Mary M MM Kachergus Jennifer M JM Sando Sigrid B SB White Linda R LR Lynch Timothy T Gibson J Mark JM Uitti Ryan J RJ Wszolek Zbigniew K ZK Aasly Jan O JO Farrer Matthew J MJ
European journal of human genetics : EJHG 20081015 3
Herein, we investigate whether single-nucleotide polymorphisms (SNPs) across the PARK10 locus are associated with susceptibility to Parkinson's disease (PD) or age at onset (AAO) of disease. One hundred and eighty-eight SNPs were genotyped across the PARK10 locus in 180 PD patients and 180 controls from central Norway (stage 1). We then used the linkage disequilibrium (LD) structure from stage 1 to select 75 SNPs for genotyping in 186 patients and 186 controls from Ireland (stage 2). Nineteen SN ...[more]