Ontology highlight
ABSTRACT:
SUBMITTER: Marquez A
PROVIDER: S-EPMC2986636 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Márquez Ana A Varadé Jezabel J Robledo Gema G Martínez Alfonso A Mendoza Juan Luis JL Taxonera Carlos C Fernández-Arquero Miguel M Díaz-Rubio Manuel M Gómez-García María M López-Nevot Miguel Angel MA de la Concha Emilio G EG Martín Javier J Urcelay Elena E
European journal of human genetics : EJHG 20090401 10
Independent genome-wide association studies highlighted the function of CLEC16A/KIAA0350 polymorphisms modifying the risk to either multiple sclerosis (rs6498169) or type 1 diabetes (rs2903692). This C-type lectin gene maps to a linkage disequilibrium block at 16p13 and a functional role of this gene could be envisaged for other immune-related conditions, such as inflammatory bowel disease (IBD). The present study, aimed at investigating the association of those two polymorphisms with IBD, inclu ...[more]