Dataset Information

J1-M267 Y lineage marks climate-driven pre-historical human displacements.

ABSTRACT: The present day distribution of Y chromosomes bearing the haplogroup J1 M267(*)G variant has been associated with different episodes of human demographic history, the main one being the diffusion of Islam since the Early Middle Ages. To better understand the modes and timing of J1 dispersals, we reconstructed the genealogical relationships among 282 M267(*)G chromosomes from 29 populations typed at 20 YSTRs and 6 SNPs. Phylogenetic analyses depicted a new genetic background consistent with climate-driven demographic dynamics occurring during two key phases of human pre-history: (1) the spatial expansion of hunter gatherers in response to the end of the late Pleistocene cooling phases and (2) the displacement of groups of foragers/herders following the mid-Holocene rainfall retreats across the Sahara and Arabia. Furthermore, J1 STR motifs previously used to trace Arab or Jewish ancestries were shown unsuitable as diagnostic markers for ethnicity.

SUBMITTER: Tofanelli S

PROVIDER: S-EPMC2986692 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature

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J1-M267 Y lineage marks climate-driven pre-historical human displacements.

Tofanelli Sergio S Ferri Gianmarco G Bulayeva Kazima K Caciagli Laura L Onofri Valerio V Taglioli Luca L Bulayev Oleg O Boschi Ilaria I Alù Milena M Berti Andrea A Rapone Cesare C Beduschi Giovanni G Luiselli Donata D Cadenas Alicia M AM Awadelkarim Khalid Dafaallah KD Mariani-Costantini Renato R Elwali Nasr Eldin NE Verginelli Fabio F Pilli Elena E Herrera Rene J RJ Gusmão Leonor L Paoli Giorgio G Capelli Cristian C

European journal of human genetics : EJHG 20090415 11

The present day distribution of Y chromosomes bearing the haplogroup J1 M267(*)G variant has been associated with different episodes of human demographic history, the main one being the diffusion of Islam since the Early Middle Ages. To better understand the modes and timing of J1 dispersals, we reconstructed the genealogical relationships among 282 M267(*)G chromosomes from 29 populations typed at 20 YSTRs and 6 SNPs. Phylogenetic analyses depicted a new genetic background consistent with clima ...[more]

PMID: 19367321

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Project description:BackgroundThe reduced rainfall in southeast Australia has placed this region's urban and rural communities on escalating water restrictions, with anthropogenic climate change forecasts suggesting that this drying trend will continue. To mitigate the stress this may place on domestic water supply, governments have encouraged the installation of large domestic water tanks in towns and cities throughout this region. These prospective stable mosquito larval sites create the possibility of the reintroduction of Ae. aegypti from Queensland, where it remains endemic, back into New South Wales and other populated centres in Australia, along with the associated emerging and re-emerging dengue risk if the virus was to be introduced.Methodology/principal findingsHaving collated the known distribution of Ae. aegypti in Australia, we built distributional models using a genetic algorithm to project Ae. aegypti's distribution under today's climate and under climate change scenarios for 2030 and 2050 and compared the outputs to published theoretical temperature limits. Incongruence identified between the models and theoretical temperature limits highlighted the difficulty of using point occurrence data to study a species whose distribution is mediated more by human activity than by climate. Synthesis of this data with dengue transmission climate limits in Australia derived from historical dengue epidemics suggested that a proliferation of domestic water storage tanks in Australia could result in another range expansion of Ae. aegypti which would present a risk of dengue transmission in most major cities during their warm summer months.Conclusions/significanceIn the debate of the role climate change will play in the future range of dengue in Australia, we conclude that the increased risk of an Ae. aegypti range expansion in Australia would be due not directly to climate change but rather to human adaptation to the current and forecasted regional drying through the installation of large domestic water storing containers. The expansion of this efficient dengue vector presents both an emerging and re-emerging disease risk to Australia. Therefore, if the installation and maintenance of domestic water storage tanks is not tightly controlled, Ae. aegypti could expand its range again and cohabit with the majority of Australia's population, presenting a high potential dengue transmission risk during our warm summers.

Dataset Information

J1-M267 Y lineage marks climate-driven pre-historical human displacements.

Publications

J1-M267 Y lineage marks climate-driven pre-historical human displacements.

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