Ontology highlight
ABSTRACT:
SUBMITTER: Peng G
PROVIDER: S-EPMC2987176 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
European journal of human genetics : EJHG 20100101 1
Despite the great success of genome-wide association studies (GWAS) in identification of the common genetic variants associated with complex diseases, the current GWAS have focused on single-SNP analysis. However, single-SNP analysis often identifies only a few of the most significant SNPs that account for a small proportion of the genetic variants and offers only a limited understanding of complex diseases. To overcome these limitations, we propose gene and pathway-based association analysis as ...[more]