Ontology highlight
ABSTRACT:
SUBMITTER: Bayes JJ
PROVIDER: S-EPMC2987944 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20091201 5959
Hybrid sterility of the heterogametic sex is one of the first postzygotic reproductive barriers to evolve during speciation, yet the molecular basis of hybrid sterility is poorly understood. We show that the hybrid male sterility gene Odysseus-site homeobox (OdsH) encodes a protein that localizes to evolutionarily dynamic loci within heterochromatin and leads to their decondensation. In Drosophila mauritiana x Drosophila simulans male hybrids, OdsH from D. mauritiana (OdsHmau) acts as a steriliz ...[more]