Ontology highlight
ABSTRACT:
SUBMITTER: O'Brien MF
PROVIDER: S-EPMC2988082 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
O'Brien M Frank MF Cronin Angel M AM Fearn Paul A PA Savage Caroline J CJ Smith Brandon B Stasi Jason J Scardino Peter T PT Fisher Gabrielle G Cuzick Jack J Møller Henrik H Oliver R Timothy RT Berney Daniel M DM Foster Christopher S CS Eastham James A JA Vickers Andrew J AJ Lilja Hans H
International journal of cancer 20110501 10
Prostate-specific antigen (PSA) dynamics have been proposed to predict outcome in men with prostate cancer. We assessed the value of PSA velocity (PSAV) and PSA doubling time (PSADT) for predicting prostate cancer-specific mortality (PCSM) in men with clinically localized prostate cancer undergoing conservative management or early hormonal therapy. From 1990 to 1996, 2,333 patients were identified, of whom 594 had two or more PSA values before diagnosis. We examined 12 definitions for PSADT and ...[more]