Synthetic riboswitches that induce gene expression in diverse bacterial species.

ABSTRACT: We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.

SUBMITTER: Topp S 

PROVIDER: S-EPMC2988590 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature