Synthetic riboswitches that induce gene expression in diverse bacterial species.
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ABSTRACT:
SUBMITTER: Topp S
PROVIDER: S-EPMC2988590 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Publications
Synthetic riboswitches that induce gene expression in diverse bacterial species.
Topp Shana S Reynoso Colleen M K CM Seeliger Jessica C JC Goldlust Ian S IS Desai Shawn K SK Murat Dorothée D Shen Aimee A Puri Aaron W AW Komeili Arash A Bertozzi Carolyn R CR Scott June R JR Gallivan Justin P JP
Applied and environmental microbiology 20101008 23
We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria. ...[more]
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