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Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats.

ABSTRACT: BACKGROUND:The Orf virus (ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochthonous Croatian Cres-breed sheep and ii) on small family goat farm. RESULTS:Sequence and phylogenetic analyses of the ORFV B2L gene showed that the Cro-Cres-12446/09 and Cro-Goat-11727/10 were not clustered together. Cro-Cres-12446/09 shared the highest similarity with ORFV NZ2 from New Zealand, and Ena from Japan; Cro-Goat-11727/10 was closest to the HuB from China and Taiping and Hoping from Taiwan. CONCLUSION:Distinct ORFV strains are circulating in Croatia. Although ORFV infections are found ubiquitously wherever sheep and goats are farmed in Croatia, this is the first information on genetic relatedness of any Croatian ORFV with other isolates around the world.

SUBMITTER: Lojkic I

PROVIDER: S-EPMC2989325 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature

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Phylogenetic analysis of Croatian orf viruses isolated from sheep and goats.

Lojkic Ivana I Cac Zeljko Z Beck Ana A Bedekovic Tomislav T Cvetnic Zeljko Z Sostaric Branko B

Virology journal 20101112

<h4>Background</h4>The Orf virus (ORFV) is the prototype of the parapoxvirus genus and it primarily causes contagious ecthyma in goats, sheep, and other ruminants worldwide. In this paper, we described the sequence and phylogenetic analysis of the B2L gene of ORFV from two natural outbreaks: i) in autochthonous Croatian Cres-breed sheep and ii) on small family goat farm.<h4>Results</h4>Sequence and phylogenetic analyses of the ORFV B2L gene showed that the Cro-Cres-12446/09 and Cro-Goat-11727/10 ...[more]

PMID: 21073725

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