Ontology highlight
ABSTRACT:
SUBMITTER: Feng Z
PROVIDER: S-EPMC2989793 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Feng Zheng Z Ting Joey J Alfonso Zeni Z Strem Brian M BM Fraser John K JK Rutenberg Joshua J Kuo Hai-Chien HC Pinkernell Kai K
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101004 12
<h4>Background</h4>Acute kidney injury (AKI) represents a major clinical problem with high mortality and limited causal treatments. The use of cell therapy has been suggested as a potential modality to improve the course and outcome of AKI.<h4>Methods</h4>We investigated the possible renoprotection of freshly isolated, uncultured adipose tissue-derived stem and regenerative cells (ADRCs) before and after cryopreservation in a rat ischemia-reperfusion (I-R) model of AKI.<h4>Results</h4>We demonst ...[more]