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Control of vascular tone by purines and pyrimidines.


ABSTRACT: In this Commentary, the roles of uridine adenosine tetraphosphate as an endothelium-derived contracting or relaxing factor described in the paper by Tölle et?al. are considered and put into the wider context of the mechanisms of control of vascular tone by purinergic signalling via receptors located on both smooth muscle and endothelial cells.

SUBMITTER: Burnstock G 

PROVIDER: S-EPMC2990152 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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Control of vascular tone by purines and pyrimidines.

Burnstock Geoffrey G  

British journal of pharmacology 20101001 3


In this Commentary, the roles of uridine adenosine tetraphosphate as an endothelium-derived contracting or relaxing factor described in the paper by Tölle et al. are considered and put into the wider context of the mechanisms of control of vascular tone by purinergic signalling via receptors located on both smooth muscle and endothelial cells. ...[more]

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