Ontology highlight
ABSTRACT:
SUBMITTER: Maurer C
PROVIDER: S-EPMC2993744 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Maurer Carlo C Panahandeh Sascha S Jungkamp Anna-Carina AC Moser Michael M Müller Matthias M
Molecular biology of the cell 20101006 23
Twin-arginine-containing signal sequences mediate the transmembrane transport of folded proteins. The cognate twin-arginine translocation (Tat) machinery of Escherichia coli consists of the membrane proteins TatA, TatB, and TatC. Whereas Tat signal peptides are recognized by TatB and TatC, little is known about molecular contacts of the mature, folded part of Tat precursor proteins. We have placed a photo-cross-linker into Tat substrates at sites predicted to be either surface-exposed or hidden ...[more]