Ontology highlight
ABSTRACT:
SUBMITTER: Kim SM
PROVIDER: S-EPMC2994829 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Kim Soo Mi SM Park Yun-Yong YY Park Eun Sung ES Cho Jae Yong JY Izzo Julie G JG Zhang Di D Kim Sang-Bae SB Lee Jeffrey H JH Bhutani Manoop S MS Swisher Stephen G SG Wu Xifeng X Coombes Kevin R KR Maru Dipen D Wang Kenneth K KK Buttar Navtej S NS Ajani Jaffer A JA Lee Ju-Seog JS
PloS one 20101130 11
<h4>Background</h4>Despite many attempts to establish pre-treatment prognostic markers to understand the clinical biology of esophageal adenocarcinoma (EAC), validated clinical biomarkers or parameters remain elusive. We generated and analyzed tumor transcriptome to develop a practical biomarker prognostic signature in EAC.<h4>Methodology/principal findings</h4>Untreated esophageal endoscopic biopsy specimens were obtained from 64 patients undergoing surgery and chemoradiation. Using DNA microar ...[more]