Methylation patterns of Brahma during spermatogenesis and oogenesis: potential implications.
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ABSTRACT:
SUBMITTER: Nagrani SR
PROVIDER: S-EPMC2995817 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Publications
Methylation patterns of Brahma during spermatogenesis and oogenesis: potential implications.
Nagrani Sohan R SR Levens Eric D ED Baxendale Vanessa V Boucheron Catherine C Chan Wai Yee WY Rennert Owen M OM
Fertility and sterility 20100817 1
To compare methylation profiles and expression levels of Brahma at different stages of spermatogenesis, and to identify the methylation pattern during oogenesis, we analyzed gene expression and methylation patterns in murine germ cells at various developmental stages. The methylation levels of CpG islands within Brahma increased during spermatogenesis and decreased during oogenesis. This change in methylation pattern correlates with the change in expression of Brahma during spermatogenesis. As t ...[more]
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