Ontology highlight
ABSTRACT:
SUBMITTER: Bullock SL
PROVIDER: S-EPMC2997434 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Bullock Simon L SL Ringel Inbal I Ish-Horowicz David D Lukavsky Peter J PJ
Nature structural & molecular biology 20100516 6
Microtubule-based mRNA transport is widely used to restrict protein expression to specific regions in the cell and has important roles in defining cell polarity and axis determination as well as in neuronal function. However, the structural basis of recognition of cis-acting mRNA localization signals by motor complexes is poorly understood. We have used NMR spectroscopy to describe the first tertiary structure to our knowledge of an RNA element responsible for mRNA transport. The Drosophila mela ...[more]