Novel 'hunting' method using transcranial magnetic stimulation over parietal cortex disrupts visuospatial sensitivity in relation to motor thresholds.

ABSTRACT: There is considerable inter-study and inter-individual variation in the scalp location of parietal sites where transcranial magnetic stimulation (TMS) may modulate visuospatial behaviours (e.g. see Ryan, Bonilha, & Jackson, 2006); and no clear consensus on methods for identifying such sites. Here we introduce a novel TMS "hunting paradigm" that allows rapid, reliable identification of a site over the right anterior intraparietal sulcus (IPS), where short trains (at 10 Hz for 0.5 s) of TMS disrupt performance of a visuospatial task. The task involves detection of a small peripheral gap (at 14 degrees eccentricity), on one or other (known) side of an extended (29 degrees ) horizontal line centred on fixation. Signal-detection analysis confirmed that TMS at the right IPS site reduced sensitiv

SUBMITTER: Oliver R 

PROVIDER: S-EPMC2997694 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature