Ontology highlight
ABSTRACT:
SUBMITTER: Lohman-Payne B
PROVIDER: S-EPMC2998888 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Lohman-Payne Barb B Slyker Jennifer J Rowland-Jones Sarah L SL
Clinics in perinatology 20101201 4
Despite more than 2 decades of research, an effective vaccine that can prevent HIV-1 infection in populations exposed to the virus remains elusive. In the pursuit of an HIV-1 vaccine, does prevention of exposure to maternal HIV-1 in utero, at birth or in early life through breast milk require special consideration? This article reviews what is known about the immune mechanisms of susceptibility and resistance to mother-to-child transmission (MTCT) of HIV-1 and summarizes studies that have used p ...[more]