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Tick-borne encephalitis with hemorrhagic syndrome, Novosibirsk region, Russia, 1999.

ABSTRACT: Eight fatal cases of tick-borne encephalitis with an unusual hemorrhagic syndrome were identified in 1999 in the Novosibirsk Region, Russia. To study these strains, we sequenced cDNA fragments of protein E gene from six archival formalin-fixed brain samples. Phylogenetic analysis showed tick-borne encephalitis variants clustered with a Far Eastern subtype (homology 94.7%) but not with the Siberian subtype (82%).

SUBMITTER: Ternovoi VA

PROVIDER: S-EPMC3000154 | biostudies-literature | 2003 Jun

REPOSITORIES: biostudies-literature

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Tick-borne encephalitis with hemorrhagic syndrome, Novosibirsk region, Russia, 1999.

Ternovoi Vladimir A VA Kurzhukov Gennady P GP Sokolov Yuri V YV Ivanov Gennady Y GY Ivanisenko Vladimir A VA Loktev Alexander V AV Ryder Robert W RW Netesov Sergey V SV Loktev Valery B VB

Emerging infectious diseases 20030601 6

Eight fatal cases of tick-borne encephalitis with an unusual hemorrhagic syndrome were identified in 1999 in the Novosibirsk Region, Russia. To study these strains, we sequenced cDNA fragments of protein E gene from six archival formalin-fixed brain samples. Phylogenetic analysis showed tick-borne encephalitis variants clustered with a Far Eastern subtype (homology 94.7%) but not with the Siberian subtype (82%). ...[more]

PMID: 12781020

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