Ontology highlight
ABSTRACT:
SUBMITTER: Bao L
PROVIDER: S-EPMC3001472 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
PloS one 20101213 12
Systems genetics studies often involve the mapping of numerous regulatory relations between genetic loci and expression traits. These regulatory relations form a bipartite network consisting of genetic loci and expression phenotypes. Modular network organizations may arise from the pleiotropic and polygenic regulation of gene expression. Here we analyzed the expression QTL (eQTL) networks derived from expression genetic data of yeast and mouse liver and found 65 and 98 modules respectively. Comp ...[more]