Ontology highlight
ABSTRACT:
SUBMITTER: Rasmussen MD
PROVIDER: S-EPMC3002250 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Rasmussen Matthew D MD Kellis Manolis M
Molecular biology and evolution 20100725 1
Recent sequencing and computing advances have enabled phylogenetic analyses to expand to both entire genomes and large clades, thus requiring more efficient and accurate methods designed specifically for the phylogenomic context. Here, we present SPIMAP, an efficient Bayesian method for reconstructing gene trees in the presence of a known species tree. We observe many improvements in reconstruction accuracy, achieved by modeling multiple aspects of evolution, including gene duplication and loss ...[more]