Ontology highlight
ABSTRACT:
SUBMITTER: Itadani A
PROVIDER: S-EPMC3008279 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Itadani Akiko A Nakamura Taro T Hirata Aiko A Shimoda Chikashi C
Eukaryotic cell 20100910 12
Calmodulin in Schizosaccharomyces pombe is encoded by the cam1(+) gene, which is indispensable for both vegetative growth and sporulation. Here, we report how Cam1 functions in spore formation. We found that Cam1 preferentially localized to the spindle pole body (SPB) during meiosis and sporulation. Formation of the forespore membrane, a precursor of the plasma membrane in spores, was blocked in a missense cam1 mutant, which was viable but unable to sporulate. Three SPB proteins necessary for th ...[more]