Ontology highlight
ABSTRACT:
SUBMITTER: Qi HF
PROVIDER: S-EPMC3009102 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Structure reports online 20101030 Pt 11
In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti-tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di-methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim-idine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of mol-ecules related by twofold rotational symmetry are linked into dimers through π-π inter-actions between the indazole ring systems [centroid-centroid distance = 3.720 (2) Å]. Weak in ...[more]