Unknown

Dataset Information

0

N-(2-Chloro-pyrimidin-4-yl)-N,2-di-methyl-2H-indazol-6-amine.


ABSTRACT: In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti-tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di-methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim-idine fragments form a dihedral angle of 62.63?(5)°. In the crystal, pairs of mol-ecules related by twofold rotational symmetry are linked into dimers through ?-? inter-actions between the indazole ring systems [centroid-centroid distance = 3.720?(2)?Å]. Weak inter-molecular C-H?N hydrogen bonds further assemble these dimers into columns propagated in [001].

SUBMITTER: Qi HF 

PROVIDER: S-EPMC3009102 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

N-(2-Chloro-pyrimidin-4-yl)-N,2-di-methyl-2H-indazol-6-amine.

Qi Hao-Fei HF   Liu Bing-Ni BN   Liu Mo M   Liu Deng-Ke DK  

Acta crystallographica. Section E, Structure reports online 20101030 Pt 11


In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti-tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di-methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim-idine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of mol-ecules related by twofold rotational symmetry are linked into dimers through π-π inter-actions between the indazole ring systems [centroid-centroid distance = 3.720 (2) Å]. Weak in  ...[more]

Similar Datasets

| S-EPMC3120303 | biostudies-literature
| S-EPMC2977289 | biostudies-literature
| S-EPMC3379441 | biostudies-other
| S-EPMC5730312 | biostudies-literature
| S-EPMC3007855 | biostudies-literature
| S-EPMC3884430 | biostudies-literature
| S-EPMC2980157 | biostudies-literature
| S-EPMC3212268 | biostudies-literature
| S-EPMC3569258 | biostudies-literature
| S-EPMC3589031 | biostudies-other