Epigenetics gets sweeter: O-GlcNAc joins the "histone code".

ABSTRACT: O-GlcNAcylation has now been added to the growing list of histone modifications making up the multifaceted "histone-code" (Sakabe et al., 2010). The sites of O-GlcNAc-histone modification hint at a role in chromatin remodeling, thus adding to mounting evidence that O-GlcNAc cycling sits atop a robust regulatory network maintaining higher-order chromatin structure and epigenetic memory.

SUBMITTER: Hanover JA 

PROVIDER: S-EPMC3010756 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature