Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays.
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SUBMITTER: Miki R
PROVIDER: S-EPMC30115 | biostudies-literature | 2001 Feb
REPOSITORIES: biostudies-literature
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Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays.
Miki R R Kadota K K Bono H H Mizuno Y Y Tomaru Y Y Carninci P P Itoh M M Shibata K K Kawai J J Konno H H Watanabe S S Sato K K Tokusumi Y Y Kikuchi N N Ishii Y Y Hamaguchi Y Y Nishizuka I I Goto H H Nitanda H H Satomi S S Yoshiki A A Kusakabe M M DeRisi J L JL Eisen M B MB Iyer V R VR Brown P O PO Muramatsu M M Shimada H H Okazaki Y Y Hayashizaki Y Y
Proceedings of the National Academy of Sciences of the United States of America 20010201 5
We have systematically characterized gene expression patterns in 49 adult and embryonic mouse tissues by using cDNA microarrays with 18,816 mouse cDNAs. Cluster analysis defined sets of genes that were expressed ubiquitously or in similar groups of tissues such as digestive organs and muscle. Clustering of expression profiles was observed in embryonic brain, postnatal cerebellum, and adult olfactory bulb, reflecting similarities in neurogenesis and remodeling. Finally, clustering genes coding fo ...[more]
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