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3-Ethyl 2-methyl 8-bromo-2-phenyl-1,2,3,3a,4,9b-hexa-hydro-chromeno[4,3-b]pyrrole-2,3-dicarboxyl-ate.

ABSTRACT: The title compound, C(22)H(22)BrNO(5), was synthesized by the intra-molecular cyclo-addition reaction of (E)-ethyl 4-(4-bromo-2-formyl-phen-oxy)but-2-enoate and methyl 2-amino-2-phenyl-acetate. The pyrrolidine and 3,4-dihydro-2H-pyran rings exhibit envelope conformations. The two benzene rings are twisted to each other at a dihedral angle of 59.36?(18)°. The eth-oxy group of the ester unit is disordered over two sites with an occupancy ratio of 0.503?(11):0.497?(11). Weak inter-molecular C-H?O hydrogen bonding is present in the crystal structure.

SUBMITTER: He L

PROVIDER: S-EPMC3011766 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature

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3-Ethyl 2-methyl 8-bromo-2-phenyl-1,2,3,3a,4,9b-hexa-hydro-chromeno[4,3-b]pyrrole-2,3-dicarboxyl-ate.

He Long L

Acta crystallographica. Section E, Structure reports online 20101106 Pt 12

The title compound, C(22)H(22)BrNO(5), was synthesized by the intra-molecular cyclo-addition reaction of (E)-ethyl 4-(4-bromo-2-formyl-phen-oxy)but-2-enoate and methyl 2-amino-2-phenyl-acetate. The pyrrolidine and 3,4-dihydro-2H-pyran rings exhibit envelope conformations. The two benzene rings are twisted to each other at a dihedral angle of 59.36 (18)°. The eth-oxy group of the ester unit is disordered over two sites with an occupancy ratio of 0.503 (11):0.497 (11). Weak inter-molecular C-H⋯O h ...[more]

PMID: 21589384

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