Ontology highlight
ABSTRACT:
SUBMITTER: Pabit SA
PROVIDER: S-EPMC3012602 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Pabit Suzette A SA Meisburger Steve P SP Li Li L Blose Joshua M JM Jones Christopher D CD Pollack Lois L
Journal of the American Chemical Society 20101103 46
The majority of charge-compensating ions around nucleic acids form a diffuse counterion "cloud" that is not amenable to investigation by traditional methods that rely on rigid structural interactions. Although various techniques have been employed to characterize the ion atmosphere around nucleic acids, only anomalous small-angle X-ray scattering (ASAXS) provides information about the spatial distribution of ions. Here we present an experimentally straightforward extension of ASAXS that can be u ...[more]