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The Protein Ontology: a structured representation of protein forms and complexes.

ABSTRACT: The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein research. PRO (http://pir.georgetown.edu/pro) is part of the Open Biomedical Ontology Foundry.

SUBMITTER: Natale DA

PROVIDER: S-EPMC3013777 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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The Protein Ontology: a structured representation of protein forms and complexes.

Natale Darren A DA Arighi Cecilia N CN Barker Winona C WC Blake Judith A JA Bult Carol J CJ Caudy Michael M Drabkin Harold J HJ D'Eustachio Peter P Evsikov Alexei V AV Huang Hongzhan H Nchoutmboube Jules J Roberts Natalia V NV Smith Barry B Zhang Jian J Wu Cathy H CH

Nucleic acids research 20101008 Database issue

The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate repres ...[more]

PMID: 20935045

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The representation of protein complexes in the Protein Ontology (PRO).

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