Ontology highlight
ABSTRACT:
SUBMITTER: Albarino CG
PROVIDER: S-EPMC3014187 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Albariño César G CG Bird Brian H BH Chakrabarti Ayan K AK Dodd Kimberly A KA White David M DM Bergeron Eric E Shrivastava-Ranjan Punya P Nichol Stuart T ST
Journal of virology 20101027 1
The Arenaviridae are a diverse and globally distributed collection of viruses that are maintained primarily by rodent reservoirs. Junin virus (JUNV) and Lassa virus (LASV) can both cause significant outbreaks of severe and often fatal human disease throughout their respective areas of endemicity. In an effort to improve upon the existing live attenuated JUNV Candid1 vaccine, we generated a genetically homogenous stock of this virus from cDNA copies of the virus S and L segments by using a revers ...[more]