Ontology highlight
ABSTRACT:
SUBMITTER: Jia Y
PROVIDER: S-EPMC3014525 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Jia Yanbin Y Persson Christina C Hou Lifang L Zheng Zongli Z Yeager Meredith M Lissowska Jolanta J Chanock Stephen J SJ Chow Wong-Ho WH Ye Weimin W
Cancer causes & control : CCC 20100201 2
<h4>Objective</h4>MUC1, MUC5AC, and MUC6 are main constituents of the mucus barrier in the stomach, which protects the underlying epithelium from acid, proteases, mechanical trauma, and pathogenic microorganisms. Accumulating evidence implicates potential roles of MUC1, MUC5AC, and MUC6 genetic variation in the development of stomach cancer.<h4>Methods</h4>We evaluated the relationship between common genetic variations in these genes and stomach cancer risk, using an LD-based tagSNP approach in ...[more]