Ontology highlight
ABSTRACT:
SUBMITTER: de Saldanha da Gama Fischer J
PROVIDER: S-EPMC3017632 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
de Saldanha da Gama Fischer Juliana J Costa Carvalho Paulo P da Fonseca Clovis Orlando CO Liao Lujian L Degrave Wim M WM da Gloria da Costa Carvalho Maria M Yates John R JR Domont Gilberto B GB
Journal of proteome research 20100927 1
Glioblastoma multiform (GBM) is by far the most malignant glioma. We have introduced a new treatment for GBMs that comprises the inhalation of a naturally occurring terpene with chemotherapeutic properties known as perillyl alcohol (POH). Clinical trial results on recurrent GBM patients showed that POH extends the average life by more than eight months, temporarily slows tumor growth, and in some cases even decreases tumor size. After approximately seven months, the tumor continues to grow and l ...[more]