Ontology highlight
ABSTRACT:
SUBMITTER: Rose CE
PROVIDER: S-EPMC3019776 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Rose Charles E CE Romero-Steiner Sandra S Burton Robert L RL Carlone George M GM Goldblatt David D Nahm Moon H MH Ashton Lindsey L Haston Mitch M Ekström Nina N Haikala Raili R Käyhty Helena H Henckaerts Isabelle I Durant Nathalie N Poolman Jan T JT Fernsten Phil P Yu Xinhong X Hu Branda T BT Jansen Kathrin U KU Blake Milan M Simonetti Elles R ER Hermans Peter W M PW Plikaytis Brian D BD
Clinical and vaccine immunology : CVI 20101117 1
Antibody-mediated killing of Streptococcus pneumoniae (pneumococcus) by phagocytes is an important mechanism of protection of the human host against pneumococcal infections. Measurement of opsonophagocytic antibodies by use of a standardized opsonophagocytic assay (OPA) is important for the evaluation of candidate vaccines and required for the licensure of new pneumococcal conjugate vaccine formulations. We assessed agreement among six laboratories that used their own optimized OPAs on a panel o ...[more]