Ontology highlight
ABSTRACT:
SUBMITTER: Tonthat NK
PROVIDER: S-EPMC3020112 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Tonthat Nam Ky NK Arold Stefan T ST Pickering Brian F BF Van Dyke Michael W MW Liang Shoudan S Lu Yue Y Beuria Tushar K TK Margolin William W Schumacher Maria A MA
The EMBO journal 20101126 1
In Escherichia coli, cytokinesis is orchestrated by FtsZ, which forms a Z-ring to drive septation. Spatial and temporal control of Z-ring formation is achieved by the Min and nucleoid occlusion (NO) systems. Unlike the well-studied Min system, less is known about the anti-DNA guillotining NO process. Here, we describe studies addressing the molecular mechanism of SlmA (synthetic lethal with a defective Min system)-mediated NO. SlmA contains a TetR-like DNA-binding fold, and chromatin immunopreci ...[more]