Ontology highlight
ABSTRACT:
SUBMITTER: Duggin IG
PROVIDER: S-EPMC3020120 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Duggin Iain G IG Dubarry Nelly N Bell Stephen D SD
The EMBO journal 20101126 1
Archaea of the genus Sulfolobus have a single-circular chromosome with three replication origins. All three origins fire in every cell in every cell cycle. Thus, three pairs of replication forks converge and terminate in each replication cycle. Here, we report 2D gel analyses of the replication fork fusion zones located between origins. These indicate that replication termination involves stochastic fork collision. In bacteria, replication termination is linked to chromosome dimer resolution, a ...[more]