Ontology highlight
ABSTRACT:
SUBMITTER: Agrawal NJ
PROVIDER: S-EPMC3020790 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Agrawal Neeraj J NJ Weinstein Joshua J Radhakrishnan Ravi R
Molecular physics 20080801 15
Using a recently developed multiscale simulation methodology, we describe the equilibrium behaviour of bilayer membranes under the influence of curvature-inducing proteins using a linearized elastic free energy model. In particular, we describe how the cooperativity associated with a multitude of protein-membrane interactions and protein diffusion on a membrane-mediated energy landscape elicits emergent behaviour in the membrane phase. Based on our model simulations, we predict that, depending o ...[more]