Ontology highlight
ABSTRACT:
SUBMITTER: Ronald J
PROVIDER: S-EPMC3020902 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Ronald James J Rajagopalan Ramakrishnan R Cerrato Felecia F Nord Alex S AS Hatsukami Thomas T Kohler Ted T Marcovina Santica S Heagerty Patrick P Jarvik Gail P GP
Stroke 20101202 1
<h4>Background and purpose</h4>lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). The relationship between genetic variation in the LPA gene region and CAAD risk remains unknown.<h4>Methods</h4>we genotyped single nucleotide polymorphisms (SNPs) in the LPAL2, LPA, and PLG regions in 530 individuals with severe CAAD and 770 controls and kringle IV type 2 (KIV2) repeat length in a subset of 90 individuals ...[more]