Ontology highlight
ABSTRACT:
SUBMITTER: Doolan DL
PROVIDER: S-EPMC3021802 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Doolan Denise L DL Mu Yunxiang Y Unal Berkay B Sundaresh Suman S Hirst Siddiqua S Valdez Conrad C Randall Arlo A Molina Douglas D Liang Xiaowu X Freilich Daniel A DA Oloo J Aggrey JA Blair Peter L PL Aguiar Joao C JC Baldi Pierre P Davies D Huw DH Felgner Philip L PL
Proteomics 20081101 22
A complete description of the serological response following exposure of humans to complex pathogens is lacking and approaches suitable for accomplishing this are limited. Here we report, using malaria as a model, a method which elucidates the profile of antibodies that develop after natural or experimental infection or after vaccination with attenuated organisms, and which identifies immunoreactive antigens of interest for vaccine development or other applications. Expression vectors encoding 2 ...[more]