Ontology highlight
ABSTRACT:
SUBMITTER: Simmons JM
PROVIDER: S-EPMC3021956 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Simmons Janine M JM Minamimoto Takafumi T Murray Elisabeth A EA Richmond Barry J BJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 20101101 47
Subregions of prefrontal cortex are important for estimating reward values and using these values to guide behavior. The present studies directly tested whether orbital prefrontal cortex (O-PFC) and lateral prefrontal cortex (L-PFC) are necessary for evaluating trial-to-trial changes in the reward values predicted by visual cues. We have compared intact rhesus monkeys, those with bilateral O-PFC lesions (n = 3), and those with bilateral L-PFC lesions (n = 3). We used three versions of a visually ...[more]