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Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules.


ABSTRACT: An 8-(phenyl)-2'-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin.

SUBMITTER: Betancourt JE 

PROVIDER: S-EPMC3021979 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature

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Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules.

Betancourt José E JE   Subramani Chandramouleeswaran C   Serrano-Velez José L JL   Rosa-Molinar Eduardo E   Rotello Vincent M VM   Rivera José M JM  

Chemical communications (Cambridge, England) 20101025 45


An 8-(phenyl)-2'-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin. ...[more]

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