Ontology highlight
ABSTRACT:
SUBMITTER: Geblinger D
PROVIDER: S-EPMC3022145 | biostudies-literature | 2009 Jan
REPOSITORIES: biostudies-literature
Chembiochem : a European journal of chemical biology 20090101 1
Bone is continuously repaired and remodeled through the well-coordinated activity of osteoblasts, which form new bone, and osteoclasts, which resorb it. How osteoclasts sense the properties of the bone surface remains unclear. By combining light and electron microscopy, we compared osteoclast behavior on three distinct surfaces: glass, calcite single crystals, and bone. Podosomes, the basic units of the adhesion structure, and their organization into superstructures were found to be common to ce ...[more]