Ontology highlight
ABSTRACT:
SUBMITTER: Zhang K
PROVIDER: S-EPMC3022967 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Zhang Kai K Osakada Yasuko Y Xie Wenjun W Cui Bianxiao B
Microscopy research and technique 20101013 7
The dynamics of cargo movement in axons encodes crucial information about the underlying regulatory mechanisms of the axonal transport process in neurons, a central problem in understanding many neurodegenerative diseases. Quantitative analysis of cargo dynamics in axons usually includes three steps: (1) acquiring time-lapse image series, (2) localizing individual cargos at each time step, and (3) constructing dynamic trajectories for kinetic analysis. Currently, the later two steps are usually ...[more]