Ontology highlight
ABSTRACT:
SUBMITTER: Xiao Z
PROVIDER: S-EPMC3024469 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Xiao Zhongping Z Tappen Britney R BR Ly Mellisa M Zhao Wenjing W Canova Lauren P LP Guan Huashi H Linhardt Robert J RJ
Journal of medicinal chemistry 20101217 2
Seven pharmaceutical heparins were investigated by oligosaccharide mapping by digestion with heparin lyase 1, 2, or 3, followed by high performance liquid chromatography analysis. The structure of one of the prepared mapping standards, ΔUA-Gal-Gal-Xyl-O-CH(2)CONHCH(2)COOH (where ΔUA is 4-deoxy-α-l-threo-hex-4-eno-pyranosyluronic acid, Gal is β-d-galactpyranose, and Xyl is β-d-xylopyranose) released from the linkage region using either heparin lyase 2 or heparin lyase 3 digestion, is reported for ...[more]